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The Food and Drug Administration, FDA, has approved the drug Vivitrol for that treatment of opioid dependence in accordance with a news release by them on 10-12-2010.

Using two separate drugs to lose weight naturally can be very effective you will find combinations as you're watching FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it one should err along the side of caution and allow the FDA do its job and demand some investigation be done so that the public understands the side effects and risks of the medications before we drive them. Keep in mind that drug companies have been in business to generate money and that they would say almost anything to keep people on his or her medications.

Researchers found out that participants investing in this drug to get a year, dropped excess weight within 4 weeks and have kept the extra weight off through the entire 56 weeks of the study. Contrave is really a combination with the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which are made up of multiple active ingredient, that might make them far better and safer.

Combo-pilling will be the newest fad or even better the newest in the future under scrutiny and so it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills has become popular is the fact that by right now there are not any long term prescription weight loss supplements that have been approved by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be licensed by the FDA.

Seizures certainly are a side effect with Contrave and must not be taken in those with seizure disorders. The drug also can raise blood pressure levels and pulse rate, and shouldn't be used in people with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure and heartbeat and must not be used in patients with uncontrolled high hypertension, along with by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients having a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients for the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking.


The most common unwanted effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.

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